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Chemical risk: a real danger in the workplace

29 July 2025

Chemical risk is one of the main threats to workers' health and safety, especially in industrial sectors where substances such as diisocyanates and polyurethanes are used. The presence of hazardous chemicals can cause serious acute and chronic health effects, such as dermatitis, eye irritation, asthma and other damage to the respiratory system.

In Italy, Decree 81/08 requires the identification of hazards related to chemical risks, their assessment and the adoption of appropriate preventive measures: chemical risk assessment therefore becomes a fundamental step in protecting workers and ensuring a safe working environment.

Diisocyanates and polyurethanes: what they are and why they are dangerous

Diisocyanates and polyurethanes: what they are and why they are dangerous

Diisocyanates are chemical compounds used mainly in the production of polyurethane-based foams, coatings, sealants and adhesives. Although these substances are widely used due to their versatility, they pose a significant chemical hazard to health.

Exposure to diisocyanates can occur through inhalation or skin contact and can lead to severe allergic reactions and respiratory and skin sensitisation. Furthermore, incorrect use or lack of adequate training on diisocyanates greatly increases the risk of accidents and occupational diseases.

Diisocyanates and polyurethanes: what they are and why they are dangerous

The importance of training in reducing chemical risk

To prevent accidents and illnesses related to the use of diisocyanates and polyurethanes, diisocyanate training will be mandatory from 24 August 2023. A specific diisocyanate course allows workers to learn about the characteristics of the substances, the associated risks and the correct methods of handling and storage.

In addition to the course, it is essential to provide specific training that covers all the risks present in the company in depth, providing practical guidance on the correct procedures to follow in potentially dangerous situations. This type of training helps to consolidate a shared safety culture and reduce the likelihood of accidents at work.

Chemical risk assessment and the POS document

Chemical risk assessment is the first step in properly managing hazards in the workplace. This analysis must consider the type of substances used, the duration and methods of exposure, and must be updated regularly.


An essential tool for putting risk assessment into practice is the POS document (Operational Safety Plan), which is mandatory on temporary or mobile construction sites but also useful in other industrial contexts. The POS document describes in detail the safety procedures, the necessary personal protective equipment (PPE) and the emergency measures to be taken in the event of accidents.

Chemical risk assessment and the POS document

Chemical safety: an investment in corporate health

Investing in training and safety is not only a regulatory obligation, but also a strategic advantage: proper management of occupational risks reduces costs related to accidents and occupational diseases, improves productivity and helps to build a more peaceful and motivating work environment.


Effective chemical risk management requires a combination of practical and training measures. Among these, the isocyanate course, specific training and the POS document are essential tools for reducing exposure to hazardous substances, improving operator preparedness, protecting company employees and ensuring compliance with current regulations.